Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23867199 | 0.92 | SETD7 (0.39) | SETD7GPR119NR1H2MEN1ALDH1A1 | |
| SCHEMBL1499106 | 0.86 | GPR119 (0.41) | SETD7GPR119NR1H2MEN1ALDH1A1 | |
| SCHEMBL1499063 | 0.85 | NR1H2 (0.46) | SETD7GPR119NR1H2MEN1ALDH1A1 | |
| SCHEMBL3316577 | 0.85 | NR1H2 (0.46) | SETD7GPR119NR1H2MEN1ALDH1A1 | |
| SCHEMBL28722436 | 0.85 | SETD7 (0.42) | SETD7GPR119NR1H2MEN1ALDH1A1 | |
| SCHEMBL22346776 | 0.85 | NR1H2 (0.46) | SETD7GPR119NR1H2MEN1ALDH1A1 | |
| SCHEMBL15217058 | 0.85 | SETD7 (0.42) | SETD7GPR119NR1H2MEN1ALDH1A1 | |
| SCHEMBL28722434 | 0.85 | SETD7 (0.42) | SETD7GPR119NR1H2MEN1ALDH1A1 | |
| SCHEMBL3964253 | 0.83 | SMARCA2 (0.42) | SETD7GPR119NR1H2MEN1ALDH1A1 | |
| SCHEMBL3964258 | 0.83 | SMARCA2 (0.42) | SETD7GPR119NR1H2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3153511-B1 | 2-ACYLAMINOTHIAZOLE DERIVATIVE FOR USE IN THE PREVENTION OR TREATMENT OF BLADDER/URINARY TRACT DISEASES | ASTELLAS PHARMA INC (JP) | 2019-05-15 | — | — | EP | disclosed |