SCHEMBL21020567

SCHEMBL21020567

CN(c1ccc(C2CCCCC2)cc1)c1cccc2c1oc1c(F)cccc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.35
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
STAT3 P40763 5/20 0.33
PTPN2 P17706 2/20 0.33
PTPN1 P18031 2/20 0.33
PTPRS Q13332 2/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRB2 P47870 1/20 0.33
GABRA4 P48169 1/20 0.33
GABRE P78334 1/20 0.33
GABRA6 Q16445 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20650808 0.87 KMT2A (0.36) KMT2ALMNASMN1; SMN2STAT3PTPN2
SCHEMBL21019980 0.87 KMT2A (0.36) KMT2ALMNASMN1; SMN2STAT3PTPN2
SCHEMBL20650352 0.86 GABRP (0.33) KMT2ALMNASMN1; SMN2GABRPGABRD
SCHEMBL21020301 0.85 KMT2A (0.35) KMT2ALMNASMN1; SMN2STAT3PTPN2
SCHEMBL21021474 0.85 KMT2A (0.34) KMT2ALMNASMN1; SMN2STAT3PTPN2
SCHEMBL21021031 0.85 KMT2A (0.34) KMT2ALMNASMN1; SMN2STAT3PTPN2
SCHEMBL20650246 0.84 KMT2A (0.41) KMT2ALMNASMN1; SMN2STAT3PTPN2
SCHEMBL23967908 0.84 PTPN2 (0.37) KMT2ALMNASMN1; SMN2STAT3PTPN2
SCHEMBL21020575 0.84 KMT2A (0.34) KMT2ALMNASMN1; SMN2STAT3PTPN2
SCHEMBL21021461 0.84 KMT2A (0.36) KMT2ALMNASMN1; SMN2STAT3PTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed
US-20190152919-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2019-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190152919-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME OR10J3, ETV6, ESR1 KMT2A 280/4885LMNA 3923/4885SMN1; SMN2 1116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.