Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15765691 | 0.82 | PRKCI (0.59) | PRKCIHDAC8HDAC1HDAC6NPC1 | |
| SCHEMBL24505932 | 0.79 | HDAC8 (0.35) | HDAC8HDAC1HDAC6P2RX7NPC1 | |
| SCHEMBL31484336 | 0.78 | PRSS1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1363337 | 0.78 | PRSS1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7772145 | 0.78 | AKR1C3 (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL25682588 | 0.76 | HDAC8 (0.49) | HDAC8HDAC1HDAC6SMN1; SMN2TSHR | |
| SCHEMBL24502392 | 0.76 | PRKCI (0.68) | PRKCIHDAC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3113078 | 0.76 | MAPK14 (0.47) | PRKCIHDAC8HDAC1HDAC6SMN1; SMN2 | |
| SCHEMBL20226997 | 0.76 | HDAC1 (0.44) | PRKCIHDAC1HDAC6NPC1RAB9A | |
| SCHEMBL20133768 | 0.75 | PRKCI (0.32) | PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |