Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SELL | P14151 | 2/20 | 0.51 |
| ▸ | SELP | P16109 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | CASR | P41180 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SELE | P16581 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15765691 | 0.84 | PRKCI (0.59) | AKR1C3NPC1MEN1MAPTKMT2A | |
| SCHEMBL2345304 | 0.84 | HCAR3 (0.57) | HCAR3L3MBTL1ALDH1A1KDM4ENPC1 | |
| SCHEMBL2890452 | 0.83 | HCAR3 (0.61) | HCAR3L3MBTL1ALDH1A1KDM4ENPC1 | |
| SCHEMBL26292488 | 0.82 | AKR1C3 (0.53) | AKR1C3L3MBTL1SELLSELPALDH1A1 | |
| SCHEMBL4012969 | 0.82 | ALDH1A1 (0.62) | AKR1C3L3MBTL1SELLSELPALDH1A1 | |
| SCHEMBL25682588 | 0.82 | HDAC8 (0.49) | TSHRSMN1; SMN2 | |
| SCHEMBL3113078 | 0.82 | MAPK14 (0.47) | ALDH1A1KDM4EMAPTGAALMNA | |
| Hydrochloric Acid SCHEMBL1416836 | 0.81 | ALDH1A1 (0.61) | AKR1C3L3MBTL1SELLSELPALDH1A1 | |
| SCHEMBL560143 | 0.81 | L3MBTL1 (0.57) | L3MBTL1SELLSELPALDH1A1KDM4E | |
| SCHEMBL694887 | 0.81 | CYP2C9 (0.57) | L3MBTL1ALDH1A1KDM4EMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164050-A1 | COMPOUNDS AS GLP-1R AGONISTS | TERNS PHARMACEUTICALS, INC. (US) | 2023-08-31 | — | — | WO | disclosed |
| WO-2019161495-A9 | RIPK2 INHIBITORS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2019-09-19 | — | — | WO | disclosed |
| WO-2019161495-A1 | RIPK2 INHIBITORS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2019-08-29 | — | — | WO | disclosed |
| EP-3508204-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Neupharma, Inc. (US) | 2019-07-10 | — | — | EP | disclosed |
| CN-106118428-A | A kind of waterproof scratch resistant aqueous polyurethane coating and preparation method thereof | 上海乘鹰新材料有限公司 | 2016-11-16 | — | — | CN | disclosed |
| US-8633160-B2 | Small molecule inhibitors of PDZ interactions | NONO INC. (CA) | 2014-01-21 | — | — | US | disclosed |
| US-20080227684-A1 | Small Molecule Inhibitors of PDZ Interactions | NONO INC. (CA) | 2008-09-18 | — | — | US | disclosed |
| US-6265575-B1 | THROMBIN INHIBITORS | ELI LILLY AND COMPANY | 2001-07-24 | — | — | US | disclosed |
| US-6251921-B1 | ADMINISTERING THROMBIN INHIBITING DIAMINE COMPOUND TO MAMMAL | ELI LILLY AND COMPANY | 2001-06-26 | — | — | US | disclosed |
| US-6025382-A | Antithrombotic diamines | ELI LILLY AND COMPANY (US) | 2000-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227684-A1 | Small Molecule Inhibitors of PDZ Interactions | PDLIM5, DAB2IP, PSD | AKR1C3 4659/4885HCAR3 3593/4885L3MBTL1 1478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.