Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14489499 | 0.86 | IDO1 (0.75) | IDO1CYP3A4CYP2A6CYP11B1CYP11B2 | |
| SCHEMBL3071130 | 0.78 | IDO1 (0.64) | IDO1CYP3A4CYP2A6CYP11B1CYP11B2 | |
| SCHEMBL870900 | 0.78 | IDO1 (0.64) | IDO1CYP3A4CYP2A6CYP11B1CYP11B2 | |
| SCHEMBL710352 | 0.78 | IDO1 (1.00) | IDO1CYP3A4CYP2A6CYP11B1CYP11B2 | |
| SCHEMBL3152446 | 0.78 | IDO1 (0.64) | IDO1CYP3A4CYP2A6CYP11B1CYP11B2 | |
| SCHEMBL25138280 | 0.78 | IDO1 (0.64) | IDO1CYP3A4CYP2A6CYP11B1CYP11B2 | |
| SCHEMBL10346856 | 0.78 | IDO1 (0.64) | IDO1CYP3A4CYP2A6CYP11B1CYP11B2 | |
| SCHEMBL22114976 | 0.78 | IDO1 (0.64) | IDO1CYP3A4CYP2A6CYP11B1CYP11B2 | |
| SCHEMBL5546083 | 0.78 | IDO1 (0.69) | IDO1CYP3A4CYP2A6CYP11B1CYP11B2 | |
| SCHEMBL872242 | 0.78 | IDO1 (0.64) | IDO1CYP3A4CYP2A6CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3486250-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | Samsung Display Co., Ltd. (KR) | 2019-05-22 | — | — | EP | disclosed |