SCHEMBL3071130

SCHEMBL3071130

Oc1cccc(-n2ccnc2)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.64
ENPP2 Q13822 1/20 0.61
MKNK1 Q9BUB5 1/20 0.61
MKNK2 Q9HBH9 1/20 0.61
CYP3A4 P08684 2/20 0.60
CYP2A6 P11509 1/20 0.55
CYP11B1 P15538 4/20 0.54
CYP11B2 P19099 3/20 0.54
CYP19A1 P11511 2/20 0.54
CYP17A1 P05093 1/20 0.51
CYP21A2 P08686 1/20 0.51
NCOA3 Q9Y6Q9 1/20 0.49
MEN1 O00255 1/20 0.49
ALOX15 P16050 1/20 0.49
TSHR P16473 1/20 0.49
KMT2A Q03164 1/20 0.49
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
NOTUM Q6P988 1/20 0.47
PDE3B Q13370 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29483362 1.00 IDO1 (0.64) IDO1ENPP2MKNK1MKNK2CYP3A4
SCHEMBL14489499 0.86 IDO1 (0.75) IDO1ENPP2MKNK1MKNK2CYP3A4
SCHEMBL28559272 0.80 ENPP2 (0.64) IDO1ENPP2MKNK1MKNK2CYP3A4
SCHEMBL870900 0.78 IDO1 (0.64) IDO1ENPP2MKNK1MKNK2CYP3A4
SCHEMBL22114976 0.78 IDO1 (0.64) IDO1ENPP2MKNK1MKNK2CYP3A4
SCHEMBL25138280 0.78 IDO1 (0.64) IDO1ENPP2MKNK1MKNK2CYP3A4
SCHEMBL3152446 0.78 IDO1 (0.64) IDO1ENPP2MKNK1MKNK2CYP3A4
SCHEMBL21020697 0.78 IDO1 (0.64) IDO1ENPP2MKNK1MKNK2CYP3A4
SCHEMBL5546083 0.78 IDO1 (0.69) IDO1ENPP2MKNK1MKNK2CYP3A4
SCHEMBL872242 0.78 IDO1 (0.64) IDO1ENPP2MKNK1MKNK2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528905-A Methods and compositions for modulating splicing 斯基霍克疗法公司 2025-02-28 CN claimed
CN-112592666-B 360-DEG C-resistant high-temperature epoxy adhesive and preparation method and application thereof 康达新材料(集团)股份有限公司 2022-11-25 CN claimed
CN-112592666-A 360-DEG C-resistant high-temperature epoxy adhesive and preparation method and application thereof 上海康达化工新材料集团股份有限公司 2021-04-02 CN claimed
EP-0557787-B1 Imidazolylphenol derivatives, medicaments containing them and a process for the preparation of these compounds and medicaments GRUENENTHAL GMBH (DE) 2000-05-24 EP claimed
EP-0557787-A1 Imidazolylphenol derivatives, medicaments containing them and a process for the preparation of these compounds and medicaments Grünenthal GmbH (DE) 1993-09-01 EP claimed
US-4500540-A DIETETICS HOFFMANN-LA ROCHE INC. (US) 1985-02-19 US claimed
US-12522597-B2 Methods and compositions for modulating splicing SKYHAWK THERAPEUTICS, INC. (US) 2026-01-13 US disclosed
US-12509460-B2 Methods and compositions for modulating splicing SKYHAWK THERAPEUTICS, INC. (US) 2025-12-30 US disclosed
US-12319706-B2 Organometallic compound, light-emitting device including the same, and electronic apparatus including the light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2025-06-03 US disclosed
CN-119528905-A Methods and compositions for modulating splicing 斯基霍克疗法公司 2025-02-28 CN disclosed
US-12144243-B2 Organometallic compound, light-emitting device including same, and electronic apparatus including the light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2024-11-12 US disclosed
US-12035616-B2 Organic electroluminescence device and organometallic complex for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-09 US disclosed
US-12035616-B2 Organic electroluminescence device and organometallic complex for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-09 US disclosed
EP-0557787-A1 Imidazolylphenol derivatives, medicaments containing them and a process for the preparation of these compounds and medicaments Grünenthal GmbH (DE) 1993-09-01 EP disclosed
US-5194446-A Antiarthritic agents A. H. ROBINS COMPANY, INCORPORATED (US) 1993-03-16 US disclosed
US-5192785-A Sulfamates as antiglaucoma agents A. H. ROBINS COMPANY, INCORPORATED (US) 1993-03-09 US disclosed
EP-0496793-A1 ENHANCED CHEMILUMINESCENT ASSAY. BRITISH TECH GROUP (GB) 1992-08-05 EP disclosed
US-5025031-A Aryl and aryloxyalkyl sulfamate esters useful as anticonvulsants A. H. ROBINS CO., INC. (US) 1991-06-18 US disclosed
WO-1991005872-A1 ENHANCED CHEMILUMINESCENT ASSAY BRITISH TECHNOLOGY GROUP LTD (GB) 1991-05-02 WO disclosed
EP-0403185-A2 Compounds having one or more aminosulfonyloxy radicals useful as pharmaceuticals A.H. ROBINS COMPANY, INCORPORATED (US) 1990-12-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509460-B2 Methods and compositions for modulating splicing SF3B1, RTCB, RBM17 IDO1 4770/4885ENPP2 3113/4885MKNK1 2838/4885
US-12035616-B2 Organic electroluminescence device and organometallic complex for organic electroluminescence device L1CAM, EML4, EPCAM IDO1 2472/4885ENPP2 4464/4885MKNK1 3149/4885
US-12144243-B2 Organometallic compound, light-emitting device including same, and electronic apparatus including the light-emitting device GPX1, LAGE3, NFE2L2 IDO1 839/4885ENPP2 4447/4885MKNK1 3095/4885
US-12319706-B2 Organometallic compound, light-emitting device including the same, and electronic apparatus including the light-emitting device CRY1, LAGE3, LEF1 IDO1 1346/4885ENPP2 4286/4885MKNK1 3270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.