Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | PPIA | P62937 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21020711 | 0.79 | MEN1 (0.36) | SMN1; SMN2NPC1RAB9ALMNAMEN1 | |
| SCHEMBL21021560 | 0.78 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9ALMNAMEN1 | |
| SCHEMBL21021307 | 0.77 | MEN1 (0.42) | SMN1; SMN2NPC1RAB9ALMNAMEN1 | |
| SCHEMBL21021915 | 0.77 | MEN1 (0.42) | SMN1; SMN2NPC1RAB9ALMNAMEN1 | |
| SCHEMBL21020814 | 0.76 | MEN1 (0.36) | SMN1; SMN2NPC1RAB9ALMNAMEN1 | |
| SCHEMBL21021322 | 0.75 | MEN1 (0.38) | SMN1; SMN2NPC1RAB9AEPHB4TEK | |
| SCHEMBL21021207 | 0.74 | MEN1 (0.37) | SMN1; SMN2NPC1RAB9AEPHB4TEK | |
| SCHEMBL21020817 | 0.72 | MEN1 (0.33) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL20076459 | 0.72 | KMT2A (0.37) | SMN1; SMN2LMNAMEN1KMT2AMAPT | |
| SCHEMBL21022006 | 0.70 | MEN1 (0.39) | SMN1; SMN2NPC1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |