Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | TEK | Q02763 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | BCL9 | O00512 | 2/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21020626 | 0.82 | MAPK14 (0.37) | MEN1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL21021225 | 0.81 | HTT (0.38) | MEN1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL21021614 | 0.81 | MEN1 (0.32) | MEN1KMT2ALMNAHTTNPC1 | |
| SCHEMBL21020562 | 0.80 | KMT2A (0.49) | MEN1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL21022118 | 0.78 | KMT2A (0.50) | MEN1KMT2ALMNAHTTNPC1 | |
| SCHEMBL21021322 | 0.77 | MEN1 (0.38) | MEN1KMT2ALMNAHTTNPC1 | |
| SCHEMBL21020536 | 0.77 | MAPK14 (0.40) | MEN1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL21020810 | 0.76 | LMNA (0.36) | MEN1KMT2ALMNAHTTNPC1 | |
| SCHEMBL21020814 | 0.74 | MEN1 (0.36) | MEN1KMT2ALMNAHTTNPC1 | |
| SCHEMBL20076571 | 0.74 | HTT (0.39) | MEN1KMT2ALMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |