Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | OGG1 | O15527 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9230966 | 0.83 | MAPT (0.42) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL1015853 | 0.79 | CYP3A4 (0.53) | TNKS2KDM4EALDH1A1HDAC2KMT2A | |
| SCHEMBL10304735 | 0.76 | TNKS2 (0.47) | TNKS2KDM4EALDH1A1ACHEMAPK14 | |
| SCHEMBL3713935 | 0.76 | KIF11 (0.43) | KDM4EALDH1A1KIF11KMT2ALMNA | |
| SCHEMBL1015114 | 0.75 | MAPK14 (0.41) | TNKS2KDM4EALDH1A1HDAC2KMT2A | |
| SCHEMBL21100108 | 0.74 | TDP1 (0.65) | KDM4EALDH1A1HDAC2KMT2AMAPT | |
| SCHEMBL20495124 | 0.74 | PRKCI (0.44) | IKBKBHDAC2KIF11KMT2AHDAC3 | |
| SCHEMBL21416767 | 0.74 | HDAC2 (0.43) | ALDH1A1HTR6HDAC2ACHEMAPT | |
| SCHEMBL3927309 | 0.74 | HDAC8 (0.49) | KDM4EALDH1A1HDAC2KMT2ALMNA | |
| SCHEMBL1018976 | 0.74 | PTPN1 (0.52) | KDM4EALDH1A1HDAC2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |