SCHEMBL21021086

SCHEMBL21021086

C=C(Nc1ccc(C)c(-c2cc(C)cc(F)c2)c1)C1C(c2cc(C)cc(Cl)c2)C1(C)Cl

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.32
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32
RAF1 P04049 1/20 0.31
BRAF P15056 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21022178 0.85 HTT (0.31)
SCHEMBL20076548 0.84 POLB (0.34)
SCHEMBL21020695 0.81
SCHEMBL21020662 0.81 MEN1 (0.31)
SCHEMBL20076805 0.80 SLC1A3 (0.30) SLC1A3SLC1A2SLC1A1
SCHEMBL21021225 0.79 HTT (0.38) SLC1A3SLC1A2SLC1A1BRAF
SCHEMBL21021114 0.79
SCHEMBL21021239 0.77 MEN1 (0.31)
SCHEMBL21021594 0.77 POLB (0.37)
SCHEMBL20076742 0.76 MEN1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283459-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-05-22 EP disclosed