SCHEMBL20076742

SCHEMBL20076742

C=C(C)c1cc(NC(=C)C2C(c3cc(C)cc(Cl)c3)C2(C)Cl)ccc1Cl

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.31
ALDH1A1 P00352 2/20 0.31
KMT2A Q03164 2/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
RECQL P46063 1/20 0.31
CSF1R P07333 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21021736 0.90 KMT2A (0.38) MEN1ALDH1A1KMT2ALMNAGAA
SCHEMBL21021896 0.86 SLC9A1 (0.30) MEN1ALDH1A1KMT2ARECQL
SCHEMBL21021313 0.86 MEN1 (0.30) MEN1ALDH1A1KMT2ALMNAGAA
SCHEMBL20076548 0.84 POLB (0.34) MEN1ALDH1A1KMT2AGAAMAPT
SCHEMBL20076459 0.84 KMT2A (0.37) MEN1ALDH1A1KMT2ALMNAGAA
SCHEMBL20076667 0.84 GSTO1 (0.31) MEN1ALDH1A1KMT2ALMNAGAA
SCHEMBL20076454 0.84 MEN1 (0.31) MEN1ALDH1A1KMT2ALMNAGAA
SCHEMBL21021465 0.83 MEN1 (0.34) MEN1ALDH1A1KMT2ALMNAGAA
SCHEMBL21020662 0.83 MEN1 (0.31) MEN1ALDH1A1KMT2ALMNAGAA
SCHEMBL20076794 0.83 CYP2C9 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed