Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMP22 | Q01453 | 2/20 | 0.63 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | GCLC | P48506 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 2/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9163433 | 0.87 | PMP22 (0.61) | PMP22SLC1A3SLC1A2SLC1A1SLC7A5 | |
| SCHEMBL13746032 | 0.85 | PMP22 (0.63) | PMP22SLC1A3SLC1A2SLC1A1GCLC | |
| SCHEMBL5904143 | 0.85 | PMP22 (0.63) | PMP22SLC1A3SLC1A2SLC1A1GCLC | |
| SCHEMBL840666 | 0.84 | PMP22 (0.68) | PMP22SLC1A3SLC1A2SLC1A1SLC7A5 | |
| SCHEMBL13745292 | 0.84 | PMP22 (0.68) | PMP22SLC1A3SLC1A2SLC1A1SLC7A5 | |
| Buthionine Sulfoxime SCHEMBL62034 | 0.81 | PMP22 (0.59) | PMP22SLC1A3SLC1A2SLC1A1GCLC | |
| SCHEMBL9162392 | 0.81 | PMP22 (0.59) | PMP22SLC1A3SLC1A2SLC1A1SLC7A5 | |
| Buthionine Sulfoxime SCHEMBL115963 | 0.81 | PMP22 (0.59) | PMP22SLC1A3SLC1A2SLC1A1GCLC | |
| Buthionine Sulfoxime SCHEMBL121171 | 0.81 | PMP22 (0.59) | PMP22SLC1A3SLC1A2SLC1A1GCLC | |
| Buthionine Sulfoxime SCHEMBL4449935 | 0.81 | PMP22 (0.59) | PMP22SLC1A3SLC1A2SLC1A1GCLC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5476966-A | S-substituted homocysteine sulfoximines | CORNELL RESEARCH FOUNDATION, INC. (US) | 1995-12-19 | — | — | US | claimed |
| WO-1989009205-A1 | METHODS FOR DEPLETION OF GLUTATHIONE | CORNELL RESEARCH FOUNDATION, INC. (US) | 1989-10-05 | — | — | WO | claimed |
| US-8163796-B1 | Treatment of cancer by oxidation-reduction potentiation of cancerostatic dicarbonyls | BioChemical Solutions, LLC (US) | 2012-04-24 | — | — | US | disclosed |
| US-5695751-A | ADMINISTERING L-AMINO ACID OXIDASE TO REDUCE PLASMA LEVEL OF LARGE AMINO ACIDS TO ALLOW INCREASED TRANSPORT OF LARGE AMINO ACID DRUGS ACROSS BLOOD BRAIN BARRIER | CORNELL RESEARCH FOUNDATION, INC. (US) | 1997-12-09 | — | — | US | disclosed |
| US-5476966-A | S-substituted homocysteine sulfoximines | CORNELL RESEARCH FOUNDATION, INC. (US) | 1995-12-19 | — | — | US | disclosed |
| WO-1989009205-A1 | METHODS FOR DEPLETION OF GLUTATHIONE | CORNELL RESEARCH FOUNDATION, INC. (US) | 1989-10-05 | — | — | WO | disclosed |