SCHEMBL21021786

SCHEMBL21021786

C=C(C)C1C(c2cc(C)cc(Cl)c2)C1(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 3/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 1/20 0.35
RECQL P46063 1/20 0.35
HTT P42858 3/20 0.35
LMNA P02545 2/20 0.35
HPGD P15428 1/20 0.35
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21021293 0.90 MEN1 (0.35) MEN1KMT2AALDH1A1RECQLHTT
SCHEMBL20076553 0.86 SLC9A1 (0.35) SLC9A1
SCHEMBL20076360 0.86 SLC9A1 (0.38) SLC9A1
SCHEMBL20076537 0.86 SLC9A1 (0.41) SLC9A1MEN1KMT2AALDH1A1RECQL
SCHEMBL21020726 0.85 SLC9A1 (0.43) SLC9A1MEN1KMT2AALDH1A1RECQL
SCHEMBL21021619 0.84 SLC9A1 (0.33) SLC9A1
SCHEMBL21021332 0.84 SLC9A1 (0.46) SLC9A1
SCHEMBL21021898 0.83 SLC9A1 (0.35) SLC9A1MEN1KMT2ALMNAMAPT
SCHEMBL21018775 0.81 MEN1 (0.44) SLC9A1MEN1KMT2AALDH1A1RECQL
SCHEMBL21586978 0.81 MEN1 (0.44) SLC9A1MEN1KMT2AALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283459-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-05-22 EP disclosed