SCHEMBL21021871

SCHEMBL21021871

C=Cc1cc(NC(=C)C2C(c3cc(C)cc(Cl)c3)C2(Cl)Cl)ccc1C

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
ALDH1A1 P00352 1/20 0.37
RECQL P46063 1/20 0.37
HTT P42858 3/20 0.36
LMNA P02545 3/20 0.34
HPGD P15428 1/20 0.34
MAPT P10636 2/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21021326 0.93 MEN1 (0.37) MEN1KMT2AALDH1A1RECQLHTT
SCHEMBL21021535 0.92 MEN1 (0.37) MEN1KMT2AALDH1A1RECQLHTT
SCHEMBL21021214 0.92 MEN1 (0.39) MEN1KMT2AALDH1A1RECQLHTT
SCHEMBL21022206 0.91 MEN1 (0.36) MEN1KMT2AALDH1A1RECQLHTT
SCHEMBL21021607 0.86 MEN1 (0.37) MEN1KMT2AALDH1A1RECQLHTT
SCHEMBL20076458 0.84 MEN1 (0.30) MEN1KMT2AALDH1A1RECQL
SCHEMBL21021339 0.83 MEN1 (0.37) MEN1KMT2AALDH1A1RECQLHTT
SCHEMBL21021225 0.82 HTT (0.38) MEN1KMT2AALDH1A1RECQLHTT
SCHEMBL20076667 0.82 GSTO1 (0.31) MEN1KMT2AALDH1A1RECQLLMNA
SCHEMBL20076812 0.81 KMT2A (0.41) MEN1KMT2AALDH1A1RECQLHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283459-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-05-22 EP disclosed