Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21020826 | 0.85 | MEN1 (0.43) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL20076380 | 0.81 | MEN1 (0.35) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL21022205 | 0.80 | TDP1 (0.48) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL20076513 | 0.77 | MEN1 (0.36) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL21020690 | 0.76 | GAA (0.39) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL21020665 | 0.76 | NPC1 (0.38) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL21021270 | 0.75 | SMN1; SMN2 (0.44) | ALDH1A1KMT2AGAASMN1; SMN2NPC1 | |
| SCHEMBL20076985 | 0.74 | — | — | |
| SCHEMBL21021371 | 0.74 | MEN1 (0.43) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL24022917 | 0.73 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |