Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21021905 | 0.90 | RXRA (0.32) | RXRAGRIN1GRIN2BTSHRMAPK1 | |
| SCHEMBL21019005 | 0.81 | MAPT (0.40) | RXRAGRIN1GRIN2BTSHRMAPK1 | |
| SCHEMBL18144108 | 0.81 | MAPT (0.40) | RXRAGRIN1GRIN2BTSHRMAPK1 | |
| SCHEMBL18144110 | 0.81 | MAPT (0.40) | RXRAGRIN1GRIN2BTSHRMAPK1 | |
| SCHEMBL18144106 | 0.81 | MAPT (0.40) | RXRAGRIN1GRIN2BTSHRMAPK1 | |
| SCHEMBL20076432 | 0.80 | MEN1 (0.40) | TP53CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21021684 | 0.73 | TSHR (0.31) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL21022153 | 0.70 | KDM1A (0.34) | MAPK1ATML3MBTL1HTTKDM4E | |
| SCHEMBL13888659 | 0.69 | DAO (0.45) | RXRAGRIN1GRIN2BMAPK1L3MBTL1 | |
| SCHEMBL18144240 | 0.69 | MEN1 (0.41) | MAPK1MRGPRX4CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |