SCHEMBL21022136

SCHEMBL21022136

C=C(C)c1cc(NC(=C)C2C(c3cc(Cl)cc(Cl)c3)C2(O)Cl)ccc1C

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
SLC9A1 P19634 1/20 0.30
MEN1 O00255 1/20 0.30
RECQL P46063 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21022180 0.80 NPC1 (0.33) ALDH1A1MEN1RECQLKMT2A
SCHEMBL21021331 0.78 MEN1 (0.37) ALDH1A1SLC9A1MEN1RECQLKMT2A
SCHEMBL21022029 0.76 CSF1R (0.32)
SCHEMBL20076501 0.76 MAPT (0.33) ALDH1A1SLC9A1MEN1RECQLKMT2A
SCHEMBL20076998 0.76 KMT2A (0.41) ALDH1A1SLC9A1MEN1RECQLKMT2A
SCHEMBL21021736 0.76 KMT2A (0.38) ALDH1A1MEN1RECQLKMT2A
SCHEMBL21021220 0.75 CYP2C9 (0.31)
SCHEMBL20076742 0.75 MEN1 (0.31) ALDH1A1MEN1RECQLKMT2A
SCHEMBL21021307 0.74 MEN1 (0.42) ALDH1A1MEN1KMT2A
SCHEMBL21022006 0.74 MEN1 (0.39) ALDH1A1SLC9A1MEN1RECQLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283459-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-05-22 EP disclosed