Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.37 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2867635 | 0.88 | SETD7 (0.47) | FAAHMGLLABHD6SETD7DRD2 | |
| SCHEMBL4874727 | 0.77 | SETD7 (0.49) | FAAHMGLLABHD6SETD7DRD2 | |
| SCHEMBL2861222 | 0.75 | SIGMAR1 (0.53) | FAAHMGLLABHD6SETD7DRD2 | |
| SCHEMBL12854661 | 0.74 | SETD7 (0.48) | FAAHMGLLABHD6SETD7DRD2 | |
| Hydrochloric Acid SCHEMBL2864381 | 0.74 | KMT2A (0.49) | FAAHMGLLABHD6SETD7DRD2 | |
| SCHEMBL2864116 | 0.73 | SETD7 (0.42) | FAAHMGLLABHD6SETD7DRD2 | |
| SCHEMBL12854640 | 0.73 | SETD7 (0.42) | FAAHMGLLABHD6SETD7DRD2 | |
| SCHEMBL4875045 | 0.73 | SETD7 (0.42) | FAAHMGLLABHD6SETD7DRD2 | |
| SCHEMBL4897050 | 0.72 | SETD7 (0.43) | FAAHMGLLABHD6SETD7DRD2 | |
| SCHEMBL2868342 | 0.71 | SETD7 (0.49) | FAAHMGLLABHD6SETD7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3485881-A1 | PERMANENTLY CHARGED SODIUM AND CALCIUM CHANNEL BLOCKERS AS ANTI-INFLAMMATORY AGENTS | President and Fellows of Harvard College (US) | 2019-05-22 | — | — | EP | disclosed |