SCHEMBL21023276

SCHEMBL21023276

C=C(C)C(=O)Nc1ccc(OC(=O)NC(C)(C)CCOC(C)(C)CC(CC(C)(C)OCCC(C)(C)NC(=O)Oc2ccc(NC(=O)C(=C)C)cc2)(C(C)(C)OCCC(C)(C)NC(=O)Oc2ccc(NC(=O)C(=C)C)cc2)C(C)(C)OCCC(C)(C)NC(=O)Oc2ccc(NC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.36
FAAH O00519 7/20 0.35
ALDH1A1 P00352 4/20 0.35
MAPT P10636 4/20 0.35
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
RAB9A P51151 1/20 0.33
GAA P10253 4/20 0.33
HTT P42858 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TSHR P16473 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
THRB P10828 2/20 0.32
HPGD P15428 1/20 0.32
KDM4E B2RXH2 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
GLA P06280 1/20 0.32
BLM P54132 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21561029 0.92 RXFP1 (0.37) RXFP1FAAHALDH1A1MAPTMEN1
SCHEMBL20808479 0.89 RXFP1 (0.35) RXFP1FAAHALDH1A1MAPTMEN1
SCHEMBL24489623 0.88 FAAH (0.36) RXFP1FAAHALDH1A1MAPTMEN1
SCHEMBL21561127 0.88 FAAH (0.40) RXFP1FAAHALDH1A1MAPTMEN1
SCHEMBL21948654 0.85 FAAH (0.35) RXFP1FAAHALDH1A1MAPTMEN1
SCHEMBL20808498 0.85 RXFP1 (0.35) RXFP1FAAHALDH1A1MAPTMEN1
SCHEMBL21656701 0.82 RXFP1 (0.33) RXFP1FAAHALDH1A1MEN1KMT2A
SCHEMBL21656992 0.82 RXFP1 (0.33) RXFP1FAAHALDH1A1MEN1KMT2A
SCHEMBL24489733 0.82 FAAH (0.31) RXFP1FAAH
SCHEMBL20204431 0.82 FAAH (0.37) RXFP1FAAHALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10946100-B2 Polymers including active agents MICROVENTION, INC. (US) 2021-03-16 US disclosed
US-20190151452-A1 Polymers Including Active Agents MICROVENTION, INC. 2019-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190151452-A1 Polymers Including Active Agents MFAP1, VCL, ACTB RXFP1 4180/4885FAAH 4139/4885ALDH1A1 4019/4885
US-10946100-B2 Polymers including active agents MFAP1, VCL, ACTB RXFP1 4180/4885FAAH 4139/4885ALDH1A1 4019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.