Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | IL1B | P01584 | 9/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18164015 | 0.92 | GAA (0.38) | GAAIL1BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL21024096 | 0.84 | GAA (0.44) | GAANR3C2 | |
| SCHEMBL18164107 | 0.84 | GAA (0.41) | GAANR3C2L3MBTL1 | |
| SCHEMBL16805955 | 0.82 | ALOX15 (0.45) | GAAHTR2ANR3C2 | |
| SCHEMBL12912163 | 0.82 | GAA (0.43) | GAANR3C2 | |
| SCHEMBL21780763 | 0.80 | GAA (0.40) | GAANR3C2L3MBTL1 | |
| SCHEMBL18164008 | 0.76 | GAA (0.38) | GAAIL1BNLRP3KHK | |
| SCHEMBL21023806 | 0.75 | KDM5A (0.39) | GAANR3C2 | |
| SCHEMBL21023691 | 0.75 | GAA (0.37) | GAANR3C2 | |
| SCHEMBL18163932 | 0.75 | KDM5A (0.43) | GAANR3C2KHKL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080087-B1 | N-SUBSTITUTED PYRAZOLYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORP (US) | 2019-05-22 | — | — | EP | disclosed |