Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 8/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14865782 | 0.80 | EPHX1 (0.76) | EPHX1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL12196200 | 0.71 | EPHX1 (1.00) | EPHX1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8303337 | 0.70 | EPHX1 (0.77) | EPHX1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14860025 | 0.70 | NPC1 (0.74) | EPHX1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL29779494 | 0.70 | SMN1; SMN2 (0.65) | EPHX1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2351318 | 0.68 | RAB9A (0.70) | EPHX1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL21741924 | 0.67 | NPC1 (0.68) | EPHX1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL16587394 | 0.67 | RAB9A (1.00) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL16108484 | 0.67 | RAB9A (1.00) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1604644 | 0.67 | RAB9A (1.00) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080087-B1 | N-SUBSTITUTED PYRAZOLYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORP (US) | 2019-05-22 | — | — | EP | disclosed |