Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18164067 | 0.90 | GAA (0.37) | GAALMNATGFBR1NR3C2KDM4E | |
| SCHEMBL31389599 | 0.84 | GAA (0.37) | GAALMNATGFBR1NR3C2KDM4E | |
| SCHEMBL19954577 | 0.83 | MAP3K12 (0.31) | TGFBR1 | |
| SCHEMBL18164113 | 0.77 | GAA (0.38) | DPP4FAPDPP8GAALMNA | |
| SCHEMBL18163952 | 0.77 | MPO (0.37) | DPP4FAPDPP8GAALMNA | |
| SCHEMBL21780763 | 0.77 | GAA (0.40) | DPP4FAPDPP8GAALMNA | |
| SCHEMBL18163942 | 0.77 | GAA (0.39) | GAALMNATGFBR1NR3C2KDM4E | |
| SCHEMBL18164033 | 0.77 | GAA (0.36) | DPP4FAPDPP8GAALMNA | |
| SCHEMBL18164107 | 0.74 | GAA (0.41) | GAALMNATGFBR1NR3C2KDM4E | |
| SCHEMBL21024096 | 0.74 | GAA (0.44) | GAALMNATGFBR1NR3C2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080087-B1 | N-SUBSTITUTED PYRAZOLYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORP (US) | 2019-05-22 | — | — | EP | disclosed |