SCHEMBL21024698

SCHEMBL21024698

CCCCC1(CCCC)c2cc(OC)ccc2-c2ccc(C(=O)C(C)(C)N3CCOCC3)cc21

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.42
ALDH1A1 P00352 8/20 0.42
TSHR P16473 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MAPK1 P28482 1/20 0.42
MAPT P10636 3/20 0.37
THRB P10828 2/20 0.37
LMNA P02545 2/20 0.37
KMT2A Q03164 1/20 0.37
KDM4E B2RXH2 1/20 0.37
HTT P42858 1/20 0.37
POLB P06746 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
GLA P06280 1/20 0.36
THRA P10827 1/20 0.36
USP2 O75604 1/20 0.36
ALOX12 P18054 1/20 0.36
HPGD P15428 1/20 0.36
PDK2 Q15119 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23805904 0.91 ALDH1A1 (0.36) ALDH1A1TSHRSMN1; SMN2MAPTTHRB
SCHEMBL23805885 0.90 CNR1 (0.39) HRH3ALDH1A1SMN1; SMN2MAPTTHRB
SCHEMBL22474742 0.87 ALDH1A1 (0.44) HRH3ALDH1A1TSHRSMN1; SMN2MAPK1
SCHEMBL29987669 0.87 ALDH1A1 (0.44) HRH3ALDH1A1TSHRSMN1; SMN2MAPK1
SCHEMBL30569665 0.87 ALDH1A1 (0.44) HRH3ALDH1A1TSHRSMN1; SMN2MAPK1
SCHEMBL23805898 0.86 ALDH1A1 (0.43) HRH3ALDH1A1TSHRSMN1; SMN2MAPK1
SCHEMBL23805900 0.85 ALDH1A1 (0.42) HRH3ALDH1A1TSHRSMN1; SMN2MAPK1
SCHEMBL21024767 0.85 ALDH1A1 (0.57) HRH3ALDH1A1TSHRSMN1; SMN2MAPK1
SCHEMBL21024706 0.85 ALDH1A1 (0.44) HRH3ALDH1A1TSHRSMN1; SMN2MAPK1
SCHEMBL23254187 0.85 ALDH1A1 (0.42) HRH3ALDH1A1TSHRSMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3514135-B1 FLUORENE PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION HAVING SAME, AND USE OF SAME IN PHOTOCURING FIELD CHANGZHOU TRONLY ADVANCED ELECTRONIC MAT CO LTD (CN) 2021-04-21 EP disclosed
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO , LTD. (CN) 2021-04-13 US disclosed
EP-3514135-A1 FLUORENE PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION HAVING SAME, AND USE OF SAME IN PHOTOCURING FIELD Changzhou Tronly Advanced Electronic Materials Co., Ltd. (CN) 2019-07-24 EP disclosed
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field CHANGZHOU TRONLY NEW ELECTRONIC MATERIALS CO., LTD. (CN) 2019-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field FAR1, AFF1, C1S HRH3 2526/4885ALDH1A1 1364/4885TSHR 3741/4885
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field FAR1, AFF1, C1S HRH3 2526/4885ALDH1A1 1364/4885TSHR 3741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.