SCHEMBL21024699

SCHEMBL21024699

CC1(C)c2cc(C(=O)C(C)(C)N3CCOCC3)ccc2-c2ccc(N3CCOCC3)cc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.48
▸ MAPK1 P28482 2/20 0.48
▸ SMN1; SMN2 Q16637 2/20 0.48
▸ TSHR P16473 1/20 0.48
▸ PDK2 Q15119 2/20 0.46
▸ MAPT P10636 4/20 0.42
▸ LMNA P02545 2/20 0.42
▸ PRKDC P78527 3/20 0.41
▸ ALK Q9UM73 1/20 0.41
▸ GSK3B P49841 1/20 0.40
▸ KMO O15229 1/20 0.40
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ ATM Q13315 1/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ PKM P14618 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ EPHX2 P34913 1/20 0.38
▸ NR1H4 Q96RI1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23805894 0.95 PDK2 (0.44) ALDH1A1MAPK1SMN1; SMN2TSHRPDK2
SCHEMBL23805871 0.92 ALDH1A1 (0.56) ALDH1A1MAPK1SMN1; SMN2TSHRPDK2
SCHEMBL21025029 0.86 ALDH1A1 (0.50) ALDH1A1MAPK1SMN1; SMN2TSHRPDK2
SCHEMBL23805901 0.86 ALDH1A1 (0.50) ALDH1A1MAPK1SMN1; SMN2TSHRLMNA
SCHEMBL21024770 0.83 ALDH1A1 (0.66) ALDH1A1MAPK1SMN1; SMN2TSHRMAPT
SCHEMBL9680425 0.81 ALDH1A1 (0.68) ALDH1A1MAPK1SMN1; SMN2TSHRMAPT
SCHEMBL21183154 0.81 SMN1; SMN2 (0.40) ALDH1A1MAPK1SMN1; SMN2TSHRPDK2
SCHEMBL21024691 0.81 ALDH1A1 (0.53) ALDH1A1MAPK1SMN1; SMN2TSHRLMNA
SCHEMBL9679918 0.79 ALDH1A1 (0.64) ALDH1A1MAPK1SMN1; SMN2TSHRMAPT
SCHEMBL9679898 0.78 ALDH1A1 (0.63) ALDH1A1MAPK1SMN1; SMN2TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO , LTD. (CN) 2021-04-13 — — US disclosed
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field CHANGZHOU TRONLY NEW ELECTRONIC MATERIALS CO., LTD. (CN) 2019-05-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field FAR1, AFF1, C1S ALDH1A1 1364/4885MAPK1 3350/4885SMN1; SMN2 3266/4885
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field FAR1, AFF1, C1S ALDH1A1 1364/4885MAPK1 3350/4885SMN1; SMN2 3266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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