SCHEMBL21024705

SCHEMBL21024705

CCCC1(CCC)c2cc(C(=O)C(C)(C)N3CCOCC3)ccc2-c2ccc(N(CC)CC)cc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
MAPK1 P28482 3/20 0.45
TSHR P16473 1/20 0.45
KDM4E B2RXH2 6/20 0.36
MAPT P10636 6/20 0.36
NPC1 O15118 4/20 0.36
RAB9A P51151 3/20 0.36
HRH3 Q9Y5N1 1/20 0.35
GBA1 P04062 1/20 0.34
MEN1 O00255 3/20 0.33
HPGD P15428 3/20 0.33
KMT2A Q03164 3/20 0.33
GAA P10253 2/20 0.33
MLYCD O95822 2/20 0.33
HTT P42858 2/20 0.33
HSD17B10 Q99714 2/20 0.33
GLA P06280 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21024769 0.91 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2MAPK1TSHRKDM4E
SCHEMBL21024706 0.85 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2MAPK1TSHRKDM4E
SCHEMBL22474742 0.80 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2MAPK1TSHRHRH3
SCHEMBL30569665 0.80 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2MAPK1TSHRHRH3
SCHEMBL29987669 0.80 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2MAPK1TSHRHRH3
SCHEMBL21024767 0.80 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2MAPK1TSHRKDM4E
SCHEMBL9679472 0.79 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2MAPK1TSHRKDM4E
SCHEMBL23805898 0.79 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2MAPK1TSHRKDM4E
SCHEMBL22745169 0.78 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2MAPK1TSHRKDM4E
SCHEMBL23254187 0.78 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2MAPK1TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3514135-B1 FLUORENE PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION HAVING SAME, AND USE OF SAME IN PHOTOCURING FIELD CHANGZHOU TRONLY ADVANCED ELECTRONIC MAT CO LTD (CN) 2021-04-21 EP disclosed
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO , LTD. (CN) 2021-04-13 US disclosed
EP-3514135-A1 FLUORENE PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION HAVING SAME, AND USE OF SAME IN PHOTOCURING FIELD Changzhou Tronly Advanced Electronic Materials Co., Ltd. (CN) 2019-07-24 EP disclosed
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field CHANGZHOU TRONLY NEW ELECTRONIC MATERIALS CO., LTD. (CN) 2019-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field FAR1, AFF1, C1S ALDH1A1 1364/4885SMN1; SMN2 3266/4885MAPK1 3350/4885
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field FAR1, AFF1, C1S ALDH1A1 1364/4885SMN1; SMN2 3266/4885MAPK1 3350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.