Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 8/20 | 0.55 |
| ▸ | MMP2 | P08253 | 8/20 | 0.55 |
| ▸ | MMP9 | P14780 | 8/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15397006 | 0.87 | MAPT (0.55) | MMP1MMP2MMP9EGFRKDM4E | |
| SCHEMBL111461 | 0.85 | MMP1 (0.75) | MMP1MMP2MMP9EGFRMAOA | |
| SCHEMBL13352267 | 0.84 | MEN1 (0.66) | MMP1MMP2MMP9KDM4EKDM1A | |
| SCHEMBL111222 | 0.81 | MMP1 (0.59) | MMP1MMP2MMP9EGFR | |
| SCHEMBL15396446 | 0.80 | MMP1 (0.67) | MMP1MMP2MMP9EGFRMAOA | |
| SCHEMBL110012 | 0.80 | MEN1 (0.68) | MMP1MMP2MMP9EGFRKDM4E | |
| SCHEMBL2779401 | 0.80 | MEN1 (0.68) | MMP1MMP2MMP9EGFRKDM4E | |
| SCHEMBL111095 | 0.79 | SMN1; SMN2 (0.74) | MMP1MMP2MMP9EGFRKDM4E | |
| SCHEMBL16272298 | 0.78 | MMP1 (0.55) | MMP1MMP2MMP9EGFRKDM4E | |
| SCHEMBL15396755 | 0.78 | MMP1 (0.55) | MMP1MMP2MMP9EGFRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3485883-A1 | METHODS OF TREATING EYE DISEASES ASSOCIATED WITH INFLAMMATION AND VASCULAR PROLIFERATION | OccuRx Pty Ltd (AU) | 2019-05-22 | — | — | EP | disclosed |