Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | PPARA | Q07869 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123690 | 0.85 | PPARG (0.62) | PPARGPPARAKMT2APOLBAPEX1 | |
| SCHEMBL8071144 | 0.81 | ALOX5 (0.60) | KMT2AALOX5GAACYP2C9OR51E2 | |
| SCHEMBL3579994 | 0.79 | ALOX5 (0.66) | KMT2AALOX5POLBCYP2C9OR51E2 | |
| SCHEMBL2845251 | 0.77 | HCAR2 (0.71) | KMT2AALDH1A1 | |
| SCHEMBL10307841 | 0.76 | ALOX5 (0.77) | KMT2AALOX5POLBOR51E2ALDH1A1 | |
| SCHEMBL10879308 | 0.76 | ALOX5 (0.66) | KMT2AALOX5POLBRENCTSD | |
| SCHEMBL30873144 | 0.75 | GAA (0.55) | PPARGPPARAKMT2AGAAAPEX1 | |
| SCHEMBL27183408 | 0.75 | GAA (0.55) | PPARGPPARAKMT2AGAAAPEX1 | |
| SCHEMBL8500981 | 0.75 | ALOX5 (0.60) | KMT2AALOX5CYP2C9OR51E2ALDH1A1 | |
| SCHEMBL347209 | 0.75 | FFAR4 (0.61) | KMT2AALOX5OR51E2ALDH1A1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3485883-A1 | METHODS OF TREATING EYE DISEASES ASSOCIATED WITH INFLAMMATION AND VASCULAR PROLIFERATION | OccuRx Pty Ltd (AU) | 2019-05-22 | — | — | EP | disclosed |