Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GLI1 | P08151 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ugandensolide SCHEMBL21025899 | 0.70 | MAPK1 (0.31) | MAPK1CYP3A4KMT2ANFKB1STAT1 | |
| SCHEMBL11403009 | 0.70 | CYP19A1 (0.40) | MAPK1CYP3A4KMT2AMEN1TP53 | |
| SCHEMBL6438246 | 0.70 | CYP19A1 (0.40) | MAPK1CYP3A4KMT2AMEN1TP53 | |
| SCHEMBL14982984 | 0.61 | CYP3A4 (0.37) | MAPK1CYP3A4KMT2AMEN1LMNA | |
| SCHEMBL7811925 | 0.60 | CYP3A4 (0.33) | MAPK1CYP3A4KMT2AMEN1LMNA | |
| SCHEMBL13392646 | 0.59 | SMN1; SMN2 (0.40) | MAPK1CYP3A4KMT2AMEN1TP53 | |
| SCHEMBL21812507 | 0.58 | CHRNB2 (0.42) | CYP3A4KMT2AMEN1MAPTTSHR | |
| SCHEMBL25493699 | 0.56 | CYP3A4 (0.33) | MAPK1CYP3A4KMT2AMEN1LMNA | |
| SCHEMBL8625426 | 0.56 | CHRM2 (0.41) | KMT2AMEN1NPSR1CYP2D6CHRM2 | |
| SCHEMBL15024805 | 0.54 | MAPT (0.37) | KMT2AMEN1LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190150437-A1 | USE OF SESQUITERPENES AND THEIR ANALOGS AS GREEN INSECTICIDES FOR CONTROLLING DISEASE VECTORS AND PLANT PESTS | OHIO STATE INNOVATION FOUNDATION | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190150437-A1 | USE OF SESQUITERPENES AND THEIR ANALOGS AS GREEN INSECTICIDES FOR CONTROLLING DISEASE VECTORS AND PLANT PESTS | NOTUM, DDT, CYP51A1 | MAPK1 4776/4885CYP3A4 219/4885KMT2A 1794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.