Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | USP5 | P45974 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26838419 | 0.85 | TMEM97 (0.59) | TMEM97SIGMAR1PPARDNPC1RAB9A | |
| SCHEMBL3343582 | 0.84 | NPC1 (0.55) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL506741 | 0.82 | NPC1 (0.57) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL16935503 | 0.81 | RAB9A (0.51) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2921979 | 0.78 | TMEM97 (0.56) | TMEM97SIGMAR1PPARDNPC1RAB9A | |
| SCHEMBL17678081 | 0.78 | EPHX2 (0.59) | TMEM97SIGMAR1LMNAALDH1A1 | |
| SCHEMBL3343302 | 0.78 | HPGD (0.55) | TMEM97SIGMAR1NPC1RAB9ALMNA | |
| SCHEMBL4510569 | 0.78 | TMEM97 (0.58) | TMEM97SIGMAR1PPARDNPC1RAB9A | |
| SCHEMBL5630504 | 0.77 | MAP2K1 (0.57) | TMEM97SIGMAR1PPARDNPC1RAB9A | |
| SCHEMBL582871 | 0.76 | TMEM97 (0.57) | TMEM97SIGMAR1PPARDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190151312-A1 | HEPARAN SULFATE BIOSYNTHESIS INHIBITORS FOR THE TREATMENT OF DISEASES | BIOMARIN PHARMACEUTICAL INC. | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190151312-A1 | HEPARAN SULFATE BIOSYNTHESIS INHIBITORS FOR THE TREATMENT OF DISEASES | HPSE, GAA, MAN2B1 | TMEM97 1005/4885SIGMAR1 3139/4885CXCR4 4085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.