Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 2/20 | 0.44 |
| ▸ | ADH1A | P07327 | 2/20 | 0.44 |
| ▸ | ADH1C | P00326 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5878451 | 0.74 | ADH1B (0.44) | ADH1BADH1AADH1CADH7 | |
| SCHEMBL6065545 | 0.72 | — | — | |
| SCHEMBL11470552 | 0.69 | HTR2A (0.33) | — | |
| SCHEMBL25761255 | 0.69 | — | — | |
| SCHEMBL8619332 | 0.69 | — | — | |
| SCHEMBL18598125 | 0.67 | ADH1B (0.41) | ADH1BADH1AADH1C | |
| SCHEMBL22161350 | 0.65 | — | — | |
| SCHEMBL16384297 | 0.64 | — | — | |
| SCHEMBL10785371 | 0.64 | — | — | |
| SCHEMBL10403673 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3272754-B1 | IMIDAZOPYRROLIDINONE COMPOUNDS | NOVARTIS AG (CH) | 2019-05-29 | — | — | EP | disclosed |