SCHEMBL21026909

SCHEMBL21026909

CCCCCCCCCCCCCC(=N)OCCN(CCOC(=O)CCCCCCCCCCCCC)C(=O)CCCCN(C)C

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.63
DGKA P23743 1/20 0.49
KDM5A P29375 5/20 0.42
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
KDM4C Q9H3R0 5/20 0.39
PHF8 Q9UPP1 2/20 0.39
PAM P19021 2/20 0.39
NAAA Q02083 1/20 0.39
TSHR P16473 1/20 0.38
MAPT P10636 1/20 0.38
KDM5C P41229 1/20 0.37
KDM5B Q9UGL1 1/20 0.37
KDM4A O75164 3/20 0.37
KDM7A Q6ZMT4 1/20 0.37
KDM2A Q9Y2K7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17586392 0.92 DNM1 (0.74) DNM1DGKAKDM5APRSS1PRSS2
SCHEMBL18350966 0.91 DNM1 (0.72) DNM1DGKAKDM5APRSS1PRSS2
SCHEMBL14157454 0.90 DNM1 (0.74) DNM1DGKAKDM5APRSS1PRSS2
SCHEMBL18335339 0.88 DNM1 (0.72) DNM1DGKAKDM5APRSS1PRSS2
SCHEMBL26054432 0.88 DNM1 (0.72) DNM1DGKAKDM5APRSS1PRSS2
SCHEMBL18350965 0.87 DNM1 (0.74) DNM1DGKAKDM5APRSS1PRSS2
SCHEMBL21027726 0.86 DNM1 (0.64) DNM1DGKAKDM5APRSS1PRSS2
SCHEMBL14157552 0.85 DNM1 (0.77) DNM1DGKAKDM5APRSS1PRSS2
SCHEMBL17586403 0.85 DNM1 (0.63) DNM1DGKAMAPT
SCHEMBL15027024 0.84 DNM1 (0.66) DNM1DGKAKDM5APRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3489220-B9 LIPIDS FOR THERAPEUTIC AGENT DELIVERY FORMULATIONS NITTO DENKO CORP (JP) 2021-11-10 EP disclosed
EP-3489220-B1 LIPIDS FOR THERAPEUTIC AGENT DELIVERY FORMULATIONS NITTO DENKO CORP (JP) 2021-08-18 EP disclosed
EP-3489220-A1 LIPIDS FOR THERAPEUTIC AGENT DELIVERY FORMULATIONS Nitto Denko Corporation (JP) 2019-05-29 EP disclosed