Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 7/20 | 0.39 |
| ▸ | PPARD | Q03181 | 7/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19928728 | 0.81 | — | — | |
| SCHEMBL23584339 | 0.76 | CES2 (0.44) | CES2CES1THRBGPR84PPARG | |
| SCHEMBL18346855 | 0.76 | AKR1B1 (0.50) | CES2CES1THRBFNTAFNTB | |
| SCHEMBL25929743 | 0.75 | CES2 (0.35) | CES2CES1THRBFNTAFNTB | |
| SCHEMBL21962985 | 0.74 | CES2 (0.42) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL20408301 | 0.74 | TSHR (0.47) | TSHRALDH1A1 | |
| SCHEMBL22137361 | 0.73 | — | — | |
| SCHEMBL21834650 | 0.72 | CES2 (0.50) | CES2CES1THRBGPR84PPARG | |
| SCHEMBL2838084 | 0.72 | CES2 (0.50) | CES2CES1THRBGPR84PPARG | |
| SCHEMBL22986932 | 0.72 | CES2 (0.50) | CES2CES1THRBGPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489219-A1 | THERAPEUTIC AGENT FOR GLAUCOMA | TOA Eiyo Ltd. (JP) | 2019-05-29 | — | — | EP | disclosed |