Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21027854 | 0.83 | PTGDR2 (0.46) | PTGDR2PTGDRTBXA2RCYP2C9 | |
| SCHEMBL21027853 | 0.75 | PTGDR2 (0.46) | PTGDR2PTGDRTBXA2RCYP2C9 | |
| SCHEMBL21028289 | 0.73 | PTGDR2 (0.45) | PTGDR2PTGDRTBXA2RCYP2C9 | |
| SCHEMBL21028284 | 0.70 | HTR2A (0.46) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL21027856 | 0.70 | PTGDR2 (0.47) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL21028003 | 0.68 | PTGDR2 (0.49) | PTGDR2PTGDRTBXA2RCYP2C9 | |
| SCHEMBL21027977 | 0.67 | PTGDR2 (0.51) | PTGDR2PTGDRTBXA2RCYP2C9 | |
| SCHEMBL21027843 | 0.67 | PTGDR2 (0.51) | PTGDR2PTGDRTBXA2RCYP2C9 | |
| SCHEMBL21028331 | 0.67 | PTGDR2 (0.40) | PTGDR2PTGDRTBXA2RCYP2C9 | |
| SCHEMBL21028288 | 0.66 | PTGDR2 (0.52) | PTGDR2PTGDRTBXA2RCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489235-A1 | TRICYCLIC COMPOUND AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |