Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 9/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21027853 | 0.69 | PTGDR2 (0.46) | PTGDR2PTGDRTBXA2RCYP3A4CYP2C9 | |
| SCHEMBL21028289 | 0.69 | PTGDR2 (0.45) | PTGDR2PTGDRTBXA2RCYP3A4CYP2C9 | |
| SCHEMBL12355547 | 0.68 | PTGDR2 (0.64) | PTGDR2PTGDRTBXA2RCYP3A4CYP2C9 | |
| SCHEMBL21027872 | 0.67 | PTGDR2 (0.43) | PTGDR2PTGDRTBXA2RCYP2C9 | |
| SCHEMBL21028306 | 0.59 | PTGDR2 (0.44) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL21028080 | 0.57 | FFAR1 (0.39) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL13279620 | 0.57 | PTGDR2 (1.00) | PTGDR2PTGDR | |
| SCHEMBL3663654 | 0.57 | PTGDR2 (0.65) | PTGDR2PTGDRTBXA2RCYP3A4CYP2C9 | |
| SCHEMBL17907989 | 0.55 | PTGDR2 (0.52) | PTGDR2PTGDRTBXA2RCYP3A4CYP2C9 | |
| SCHEMBL13279597 | 0.54 | PTGDR2 (0.49) | PTGDR2PTGDRTBXA2RCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489235-A1 | TRICYCLIC COMPOUND AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |