Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 19/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21027846 | 0.76 | PTGDR2 (0.55) | PTGDR2PTGDRPTGIRTBXA2R | |
| SCHEMBL21028288 | 0.74 | PTGDR2 (0.52) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL24141360 | 0.74 | PTGDR2 (0.45) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL21028289 | 0.74 | PTGDR2 (0.45) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL21028025 | 0.72 | PTGDR2 (0.46) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL21028019 | 0.72 | PTGDR2 (0.64) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL21028022 | 0.72 | PTGDR2 (0.42) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL21028085 | 0.70 | PTGDR2 (0.43) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL21028084 | 0.69 | PTGDR2 (0.50) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL21027860 | 0.69 | PTGDR2 (0.49) | PTGDR2PTGDRTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524958-B2 | Tricyclic compound as CRTH2 inhibitor | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2022-12-13 | — | — | US | disclosed |
| US-20210403466-A1 | TRICYCLIC COMPUND AS CRTH2 INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2021-12-30 | — | — | US | disclosed |
| EP-3489235-A1 | TRICYCLIC COMPOUND AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403466-A1 | TRICYCLIC COMPUND AS CRTH2 INHIBITOR | NR3C2, CRHR2, CRHR1 | PTGDR2 152/4885PTGDR 412/4885CYSLTR2 283/4885 |
| US-11524958-B2 | Tricyclic compound as CRTH2 inhibitor | NR1H2, NR3C2, NR1H4 | PTGDR2 313/4885PTGDR 550/4885CYSLTR2 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.