Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440541 | 1.00 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3CFTRGOPC | |
| SCHEMBL1991662 | 0.88 | CYP19A1 (0.36) | SLC6A4SLC6A2SLC6A3HDAC8 | |
| SCHEMBL18175868 | 0.87 | APP (0.44) | SLC6A4SLC6A2SLC6A3CFTRGOPC | |
| SCHEMBL2956444 | 0.85 | SLC6A2 (0.63) | SLC6A4SLC6A2SLC6A3CFTRGOPC | |
| SCHEMBL20906837 | 0.83 | SLC2A1 (0.52) | TSHRAPPKMT2A | |
| SCHEMBL144 | 0.82 | SLC6A2 (0.67) | SLC6A4SLC6A2SLC6A3CFTRGOPC | |
| SCHEMBL24238297 | 0.79 | SMN1; SMN2 (0.48) | PDPK1TSHRKMT2A | |
| SCHEMBL11605599 | 0.79 | ADRA2C (0.48) | SLC6A4SLC6A2SLC6A3PDPK1TSHR | |
| SCHEMBL14160147 | 0.79 | ESR1 (0.44) | SLC6A4PDPK1KMT2ATAAR1 | |
| SCHEMBL12228792 | 0.79 | DPP4 (0.48) | PDPK1DPP4F2HTR2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190165293-A1 | ORGANIC ELECTRONIC MATERIAL | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2019-05-30 | — | — | US | disclosed |