Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | PI4KA | P42356 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.60 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.60 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.60 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | PDE8B | O95263 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4145031 | 0.81 | TP53 (0.55) | MEN1ALDH1A1KMT2ATP53CYP2C9 | |
| SCHEMBL4148488 | 0.80 | TP53 (0.66) | MEN1ALDH1A1KMT2ATP53CYP2C9 | |
| SCHEMBL4164718 | 0.80 | MEN1 (0.66) | MEN1ALDH1A1KMT2ATP53CYP2C9 | |
| SCHEMBL11457829 | 0.80 | ADORA2A (0.54) | MEN1ALDH1A1KMT2ATP53CYP2C9 | |
| SCHEMBL22082420 | 0.80 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATP53CYP2C9 | |
| SCHEMBL460736 | 0.79 | TP53 (0.55) | MEN1ALDH1A1KMT2ATP53CYP2C9 | |
| SCHEMBL10121595 | 0.79 | PI4KA (0.61) | MEN1ALDH1A1KMT2ATP53CYP2C9 | |
| SCHEMBL3913663 | 0.79 | PDE8B (0.57) | MEN1ALDH1A1KMT2ATP53CYP2C9 | |
| SCHEMBL29809280 | 0.79 | ADORA2A (0.55) | MEN1ALDH1A1KMT2ATP53CYP2C9 | |
| SCHEMBL567355 | 0.79 | ADORA2A (0.55) | MEN1ALDH1A1KMT2ATP53CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2971033-B1 | MANUFACTURING METHODS FOR PRODUCTION OF RNA TRANSCRIPTS | MODERNA THERAPEUTICS INC (US) | 2019-05-29 | — | — | EP | disclosed |