Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13900800 | 0.87 | MAPT (0.55) | SIRT5MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL3993290 | 0.86 | MAPT (0.47) | MAPTKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL7317466 | 0.84 | PDE3B (0.46) | MAPTKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL7313188 | 0.83 | LMNA (0.52) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL12992907 | 0.82 | MAPT (0.44) | SIRT5MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL7318303 | 0.82 | KDM4E (0.47) | MAPTKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL7306695 | 0.82 | PDE3B (0.47) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7315992 | 0.82 | PDE3B (0.49) | MAPTKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL10176161 | 0.82 | MAPT (0.62) | MAPTKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL7314553 | 0.81 | KDM4E (0.48) | MAPTKDM4EALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213471-A1 | SMALL MOLECULE SCREENING CELLULAR ASSAY USING MODIFIED BEADS | F. HOFFMANN-LA ROCHE AG (CH) | 2022-07-07 | — | — | US | disclosed |
| WO-2019104070-A1 | O-NITROBENZYL PHOTOCLEAVABLE BIFUNCTIONAL LINKER | NANOSTRING TECHNOLOGIES, INC. (US) | 2019-05-31 | — | — | WO | disclosed |