Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21032091 | 0.86 | KRAS (0.38) | KRASLIMK1TOP1 | |
| SCHEMBL25847629 | 0.81 | TOP1 (0.38) | KRASTOP1CDK2GSK3B | |
| SCHEMBL25847372 | 0.80 | KRAS (0.47) | KRASLIMK1 | |
| SCHEMBL21031436 | 0.79 | TOP1 (0.35) | KRASLIMK1TOP1CDK2GSK3B | |
| SCHEMBL21031396 | 0.79 | PRKDC (0.33) | TOP1 | |
| SCHEMBL21031437 | 0.78 | KRAS (0.41) | KRASLIMK1TOP1 | |
| SCHEMBL21030692 | 0.78 | TNKS (0.38) | KRASLIMK1 | |
| SCHEMBL21032364 | 0.78 | LMNA (0.36) | KRASLIMK1TOP1 | |
| SCHEMBL21032020 | 0.77 | KRAS (0.34) | KRASLIMK1 | |
| SCHEMBL25847630 | 0.75 | PARP1 (0.35) | KRASLIMK1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | IDEMITSU KOSAN CO., LTD. (JP) | 2023-07-04 | — | — | US | disclosed |
| US-20190161497-A1 | SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO., LTD. (JP) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | KCNQ2, KCNQ1, KCNQ4 | KRAS 3523/4885LIMK1 1827/4885TOP1 3497/4885 |
| US-20190161497-A1 | SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES | KCNQ2, KCNQ1, KCNQ4 | KRAS 3523/4885LIMK1 1827/4885TOP1 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.