Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21032471 | 0.95 | PTGDR2 (0.57) | PTGDR2AKR1B1PTGS1CYP2C9 | |
| SCHEMBL24179951 | 0.94 | PTGDR2 (0.56) | PTGDR2AKR1B1CYP2C9PTGDR | |
| SCHEMBL21031879 | 0.93 | PTGDR2 (0.52) | PTGDR2AKR1B1PTGS1 | |
| SCHEMBL21032884 | 0.93 | PTGDR2 (0.53) | PTGDR2AKR1B1PTGS1CYP2C9PTGDR | |
| SCHEMBL21032561 | 0.92 | PTGDR2 (0.59) | PTGDR2AKR1B1PTGS1CYP2C9PTGDR | |
| SCHEMBL24180036 | 0.91 | PTGDR2 (0.63) | PTGDR2AKR1B1PTGS1CYP2C9 | |
| SCHEMBL21031945 | 0.91 | PTGDR2 (0.63) | PTGDR2AKR1B1PTGS1CYP2C9 | |
| SCHEMBL21031946 | 0.90 | PTGDR2 (0.53) | PTGDR2AKR1B1PTGS1CYP2C9PTGDR | |
| SCHEMBL317472 | 0.88 | PTGDR2 (0.57) | PTGDR2AKR1B1PTGS1CYP2C9PTGDR | |
| SCHEMBL21032557 | 0.87 | PTGDR2 (0.54) | PTGDR2AKR1B1CYP2C9PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489233-B1 | INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2022-01-12 | — | — | EP | disclosed |
| EP-3489233-A1 | INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |