Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 7/20 | 0.56 |
| ▸ | FER | P16591 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 6/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | BTK | Q06187 | 3/20 | 0.39 |
| ▸ | KHK | P50053 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1992464 | 0.91 | SYK (0.53) | SYKFERTYK2EGFRBTK | |
| SCHEMBL1991374 | 0.90 | SYK (0.59) | SYKFERTYK2EGFRBTK | |
| SCHEMBL16976718 | 0.89 | SYK (0.51) | SYKFERTYK2EGFRBTK | |
| SCHEMBL29949561 | 0.86 | SYK (0.49) | SYKFERTYK2EGFRBTK | |
| SCHEMBL14930559 | 0.86 | SYK (0.49) | SYKFERTYK2EGFRBTK | |
| SCHEMBL12640991 | 0.84 | SYK (0.47) | SYKFERTYK2EGFRBTK | |
| SCHEMBL1988427 | 0.83 | SYK (0.51) | SYKFERTYK2EGFRBTK | |
| SCHEMBL25401343 | 0.81 | SYK (0.41) | SYKTYK2EGFRBTK | |
| SCHEMBL1992466 | 0.81 | SYK (0.53) | SYKFERTYK2EGFRBTK | |
| SCHEMBL1988424 | 0.78 | SYK (0.51) | SYKFERTYK2EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489236-A1 | PROCESS FOR THE PREPARATION OF FUSED HETEROAROMATIC PYRROLIDINONES | Takeda Pharmaceutical Company Limited (JP) | 2019-05-29 | — | — | EP | disclosed |