Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 10/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21032501 | 0.95 | CYP1A2 (0.40) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL21582857 | 0.93 | CYP11B2 (0.39) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL23347953 | 0.93 | CYP11B2 (0.39) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL22242937 | 0.92 | ABCG2 (0.41) | ABCG2ABCB1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL26055775 | 0.92 | ABCG2 (0.42) | ABCG2ABCB1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21032502 | 0.92 | ABCG2 (0.37) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL23347766 | 0.92 | CYP11B2 (0.38) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL20937084 | 0.92 | ABCG2 (0.41) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL24797955 | 0.91 | ABCG2 (0.42) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL21364862 | 0.91 | ABCG2 (0.40) | ABCG2ABCB1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019101746-A1 | ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-05-31 | — | — | WO | disclosed |