Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4868334 | 0.76 | POLB (0.59) | MAPTKMT2AMEN1L3MBTL1POLB | |
| SCHEMBL9801910 | 0.75 | POLB (0.63) | MAPTKMT2AMEN1POLBTHRB | |
| SCHEMBL6267953 | 0.75 | POLB (0.58) | KMT2AMEN1POLBTHRBSMN1; SMN2 | |
| SCHEMBL31230156 | 0.75 | POLB (0.58) | KMT2AMEN1POLBTHRBSMN1; SMN2 | |
| SCHEMBL15925412 | 0.74 | POLB (0.60) | MAPTKMT2AMEN1POLBTHRB | |
| Hydrochloric Acid SCHEMBL5612798 | 0.74 | POLB (0.57) | KMT2AMEN1POLBTHRBSMN1; SMN2 | |
| SCHEMBL14288724 | 0.73 | POLB (0.55) | MAPTKMT2AMEN1POLBTHRB | |
| SCHEMBL14288732 | 0.71 | POLB (0.53) | MAPTKMT2AMEN1POLBTHRB | |
| SCHEMBL14288744 | 0.71 | POLB (0.46) | MAPTKMT2AMEN1POLBTHRB | |
| SCHEMBL30905277 | 0.71 | POLB (0.82) | MAPTKMT2AMEN1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104201-A1 | SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY IN NON-HUMANS | Zander Therapeutics, Inc. (US) | 2019-05-31 | — | — | WO | disclosed |
| WO-2019104199-A1 | SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY | REGEN BIOPHARMA INC. (US) | 2019-05-31 | — | — | WO | disclosed |