Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30808574 | 0.92 | MAPT (0.62) | POLBGAAALDH1A1THRBMAPT | |
| SCHEMBL6267953 | 0.82 | POLB (0.58) | POLBGAATHRBMEN1KMT2A | |
| SCHEMBL31230156 | 0.82 | POLB (0.58) | POLBGAATHRBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5612798 | 0.81 | POLB (0.57) | POLBGAATHRBMEN1KMT2A | |
| SCHEMBL15925412 | 0.81 | POLB (0.60) | POLBGAATHRBMAPTTP53 | |
| SCHEMBL13749552 | 0.78 | MAPT (0.63) | POLBTHRBMAPTTP53LMNA | |
| SCHEMBL14288724 | 0.76 | POLB (0.55) | POLBGAATHRBMAPTTP53 | |
| SCHEMBL10588416 | 0.76 | MEN1 (0.64) | THRBMAPTTP53MEN1KMT2A | |
| SCHEMBL21032963 | 0.75 | MAPT (0.58) | POLBGAAALDH1A1THRBMAPT | |
| SCHEMBL30808581 | 0.75 | ALDH1A1 (0.66) | POLBGAAALDH1A1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055464-A | Cognition activators, diuretics, antiulcer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1991-10-08 | — | — | US | disclosed |