Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16167927 | 0.87 | AR (0.64) | ARPGR | |
| SCHEMBL14682059 | 0.83 | AR (0.57) | ARCYP2D6CYP2C9CYP2C19PGR | |
| SCHEMBL1387723 | 0.78 | AR (0.73) | ARPGR | |
| SCHEMBL1773488 | 0.77 | AR (0.65) | ARPGR | |
| SCHEMBL1966813 | 0.75 | AR (0.61) | ARPGR | |
| SCHEMBL629858 | 0.74 | AR (1.00) | ARCYP2D6CYP2C9CYP2C19PGR | |
| SCHEMBL7759703 | 0.73 | AR (0.62) | ARPGR | |
| SCHEMBL12117519 | 0.73 | AR (0.43) | ARPGR | |
| SCHEMBL12117925 | 0.73 | AR (0.43) | ARPGR | |
| SCHEMBL1313024 | 0.73 | AR (0.61) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10300037-B2 | SARMs and method of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2019-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10300037-B2 | SARMs and method of use thereof | SARM1, CPT1B, TNNI3 | AR 2582/4885CYP2D6 2071/4885CYP2C9 3755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.