Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19780145 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL10656434 | 0.77 | NPSR1 (0.43) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL6729528 | 0.77 | NPSR1 (0.43) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL29176089 | 0.75 | NPSR1 (0.42) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL22620309 | 0.75 | NPSR1 (0.42) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL23607713 | 0.75 | NPSR1 (0.42) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL21033575 | 0.74 | ALDH1A1 (0.39) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL516351 | 0.73 | NPSR1 (0.41) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL18723091 | 0.73 | NPSR1 (0.41) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL19609708 | 0.72 | NPSR1 (0.39) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019102494-A1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-05-31 | — | — | WO | disclosed |