Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.32 |
| ▸ | TTK | P33981 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21014272 | 0.77 | KDM4E (0.50) | PIK3CDPIK3CA | |
| SCHEMBL21033458 | 0.76 | ALDH1A3 (0.50) | MCHR1 | |
| SCHEMBL21033467 | 0.72 | ALDH1A3 (0.49) | — | |
| SCHEMBL24460225 | 0.71 | PIK3CG (0.44) | DYRK1A | |
| SCHEMBL23950397 | 0.71 | SCN10A (0.34) | PIK3CAMCHR1 | |
| SCHEMBL21033161 | 0.71 | PTGS1 (0.43) | ENPP2SUV39H2PIK3CDPIK3CADYRK1A | |
| SCHEMBL19736985 | 0.71 | SUV39H2 (0.36) | ENPP2SUV39H2HTR1DPIK3CDPIK3CA | |
| SCHEMBL24066056 | 0.69 | MCHR1 (0.33) | MCHR1 | |
| SCHEMBL22515692 | 0.68 | KLKB1 (0.34) | PIK3CA | |
| SCHEMBL14183094 | 0.62 | MAPK14 (0.48) | HTR1DPIK3CDPIK3CAAAK1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019102494-A1 | HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-05-31 | — | — | WO | disclosed |