Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21033549 | 0.91 | ELANE (0.49) | CNR1CNR2MAPTBACE1TP53 | |
| SCHEMBL21615389 | 0.88 | ELANE (0.47) | CNR1CNR2MAPTBACE1NPC1 | |
| SCHEMBL17433296 | 0.86 | ELANE (0.39) | MAPTTP53ELANEHPGDTSHR | |
| SCHEMBL20311773 | 0.85 | BACE1 (0.48) | MAPTBACE1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24180769 | 0.85 | ELANE (0.38) | CNR1CNR2BACE1ELANELMNA | |
| SCHEMBL22173805 | 0.85 | THRB (0.41) | CNR1CNR2MAPTBACE1SMN1; SMN2 | |
| SCHEMBL18104469 | 0.82 | ELANE (0.56) | MAPTBACE1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19881850 | 0.82 | ELANE (0.56) | MAPTBACE1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21614479 | 0.82 | BACE1 (0.48) | MAPTBACE1SMN1; SMN2ELANELMNA | |
| SCHEMBL22173808 | 0.81 | ELANE (0.43) | CNR1CNR2MAPTADORA3ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489329-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2022-01-12 | — | — | EP | disclosed |
| WO-2020230480-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT, AND COMPOUND | DIC株式会社 | 2020-11-19 | — | — | WO | disclosed |
| EP-3489329-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2019-05-29 | — | — | EP | disclosed |