Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 16/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035085 | 1.00 | GHSR (0.53) | GHSRMEN1KMT2AMMP1ADAM17 | |
| SCHEMBL21036276 | 1.00 | GHSR (0.53) | GHSRMEN1KMT2AMMP1ADAM17 | |
| SCHEMBL21002027 | 1.00 | GHSR (0.53) | GHSRMEN1KMT2AMMP1ADAM17 | |
| SCHEMBL21035642 | 1.00 | GHSR (0.53) | GHSRMEN1KMT2AMMP1ADAM17 | |
| SCHEMBL21035578 | 0.95 | GHSR (0.46) | GHSRMEN1KMT2AMMP1ADAM17 | |
| SCHEMBL21035126 | 0.95 | GHSR (0.46) | GHSRMEN1KMT2AMMP1ADAM17 | |
| SCHEMBL21035349 | 0.95 | GHSR (0.46) | GHSRMEN1KMT2AMMP1ADAM17 | |
| SCHEMBL21035337 | 0.93 | KMT2A (0.45) | GHSRMEN1KMT2AMMP1ADAM17 | |
| SCHEMBL21035496 | 0.91 | KMT2A (0.44) | GHSRMEN1KMT2AMMP1ADAM17 | |
| SCHEMBL21036263 | 0.91 | KMT2A (0.44) | GHSRMEN1KMT2AMMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |