Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 6/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4186691 | 0.78 | PARP15 (0.58) | PARP10PARP15PARP2GRM2HPGD | |
| SCHEMBL20325460 | 0.74 | PARP10 (0.55) | PARP10PARP15PARP2GRM2HPGD | |
| SCHEMBL21578972 | 0.74 | PARP10 (0.63) | PARP10PARP15PARP2GRM2HPGD | |
| SCHEMBL3726896 | 0.74 | PARP10 (0.63) | PARP10PARP15PARP2GRM2HPGD | |
| SCHEMBL2657957 | 0.74 | NFE2L2 (0.69) | PARP10PARP15PARP2GRM2HPGD | |
| SCHEMBL21579020 | 0.74 | PARP10 (0.58) | PARP10PARP15PARP2GRM2HPGD | |
| SCHEMBL81903 | 0.74 | PARP15 (0.58) | PARP10PARP15PARP2GRM2HPGD | |
| SCHEMBL21579077 | 0.74 | PARP10 (0.58) | PARP10PARP15PARP2GRM2HPGD | |
| SCHEMBL385757 | 0.74 | PARP10 (0.58) | PARP10PARP15PARP2GRM2HPGD | |
| SCHEMBL11125481 | 0.74 | PARP10 (0.58) | PARP10PARP15PARP2GRM2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |